Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-pentyl-1,3,4,10-tetrahydroacridin-9(2H)-one | - |
Plasmodium berghei | |
4-pentyl-1,3,4,10-tetrahydroacridin-9(2H)-one | - |
Plasmodium falciparum | |
4-pentyl-1,3,4,10-tetrahydroacridin-9(2H)-one | - |
Plasmodium vivax | |
5-(2-methyl-1H-indol-1-yl)-N-propylthiophene-2-carboxamide | - |
Plasmodium berghei | |
5-(2-methyl-1H-indol-1-yl)-N-propylthiophene-2-carboxamide | - |
Plasmodium falciparum | |
5-(2-methyl-1H-indol-1-yl)-N-propylthiophene-2-carboxamide | - |
Plasmodium vivax | |
ethyl 4-(4-ethoxybenzyl)-3,5-dimethyl-1H-pyrrole-2-carboxylate | - |
Plasmodium berghei | |
ethyl 4-(4-ethoxybenzyl)-3,5-dimethyl-1H-pyrrole-2-carboxylate | - |
Plasmodium falciparum | |
ethyl 4-(4-ethoxybenzyl)-3,5-dimethyl-1H-pyrrole-2-carboxylate | - |
Plasmodium vivax | |
N-cyclopropyl-5-(2,3-dihydro-4H-1,4-benzothiazin-4-yl)thiophene-2-carboxamide | - |
Plasmodium berghei | |
N-cyclopropyl-5-(2,3-dihydro-4H-1,4-benzothiazin-4-yl)thiophene-2-carboxamide | - |
Plasmodium falciparum | |
N-cyclopropyl-5-(2,3-dihydro-4H-1,4-benzothiazin-4-yl)thiophene-2-carboxamide | - |
Plasmodium vivax |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Plasmodium berghei | - |
- |
- |
Plasmodium falciparum | Q08210 | - |
- |
Plasmodium vivax | - |
- |
- |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00004 | - |
pH 8.0 | Plasmodium vivax | ethyl 4-(4-ethoxybenzyl)-3,5-dimethyl-1H-pyrrole-2-carboxylate | |
0.000042 | - |
pH 8.0 | Plasmodium falciparum | 5-(2-methyl-1H-indol-1-yl)-N-propylthiophene-2-carboxamide | |
0.00006 | - |
pH 8.0 | Plasmodium berghei | 5-(2-methyl-1H-indol-1-yl)-N-propylthiophene-2-carboxamide | |
0.00006 | - |
pH 8.0 | Plasmodium berghei | ethyl 4-(4-ethoxybenzyl)-3,5-dimethyl-1H-pyrrole-2-carboxylate | |
0.000083 | - |
pH 8.0 | Plasmodium falciparum | ethyl 4-(4-ethoxybenzyl)-3,5-dimethyl-1H-pyrrole-2-carboxylate | |
0.00011 | - |
pH 8.0 | Plasmodium berghei | 4-pentyl-1,3,4,10-tetrahydroacridin-9(2H)-one | |
0.00025 | - |
pH 8.0 | Plasmodium falciparum | N-cyclopropyl-5-(2,3-dihydro-4H-1,4-benzothiazin-4-yl)thiophene-2-carboxamide | |
0.00028 | - |
pH 8.0 | Plasmodium vivax | N-cyclopropyl-5-(2,3-dihydro-4H-1,4-benzothiazin-4-yl)thiophene-2-carboxamide | |
0.00034 | - |
pH 8.0 | Plasmodium falciparum | 4-pentyl-1,3,4,10-tetrahydroacridin-9(2H)-one | |
0.00038 | - |
pH 8.0 | Plasmodium berghei | N-cyclopropyl-5-(2,3-dihydro-4H-1,4-benzothiazin-4-yl)thiophene-2-carboxamide | |
0.00042 | - |
pH 8.0 | Plasmodium vivax | 5-(2-methyl-1H-indol-1-yl)-N-propylthiophene-2-carboxamide | |
0.00051 | - |
pH 8.0 | Plasmodium vivax | 4-pentyl-1,3,4,10-tetrahydroacridin-9(2H)-one |