Crystallization (Comment) | Organism |
---|---|
mutant DELTA1-29 in complex with brequinar and with atovaquone | Rattus norvegicus |
Protein Variants | Comment | Organism |
---|---|---|
DELTA1-29 | deletion of N-terminal 29 amino acids | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
atovaquone | 50% inhibition at 0.000698 mM, wild-type enzyme, 0.000904 mM, DELTA1-29 mutant | Rattus norvegicus | |
brequinar | 50% inhibition at 0.000367 mM, wild-type enzyme, 0.000127 mM, DELTA1-29 mutant | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
recombinant wild-type enzyme and N-terminally truncated form | - |
Subunits | Comment | Organism |
---|---|---|
monomer | folds into small N-terminal domain and an (alphabeta)8 barrel comprising the C-terminal domain, crystallization data | Rattus norvegicus |