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Literature summary for 1.3.5.2 extracted from

  • Takashima, E.; Inaoka, D.K.; Osanai, A.; Nara, T.; Odaka, M.; Aoki, T.; Inaka, K.; Harada, S.; Kita, K.
    Characterization of the dihydroorotate dehydrogenase as a soluble fumarate reductase in Trypanosoma cruzi (2002), Mol. Biochem. Parasitol., 122, 189-200.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Trypanosoma cruzi 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
34000
-
2 * 34000, SDS-PAGE, dynamic light scattering analysis Trypanosoma cruzi
35000
-
gel filtration Trypanosoma cruzi

Organism

Organism UniProt Comment Textmining
Trypanosoma cruzi
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Trypanosoma cruzi

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
119000
-
cosubstrate O2, pH 7.5 Trypanosoma cruzi
245000
-
cosubstrate 2,6-dichlorophenolindophenol, pH 7.5 Trypanosoma cruzi
548000
-
cosubstrate Q1, pH 7.5 Trypanosoma cruzi

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dihydroorotate + 2,6-dichlorophenolindophenol
-
Trypanosoma cruzi orotate + reduced 2,6-dichlorophenolindophenol
-
?
additional information enzyme has methylviologen-fumarate reductase activity Trypanosoma cruzi ?
-
?

Subunits

Subunits Comment Organism
homodimer 2 * 34000, SDS-PAGE, dynamic light scattering analysis Trypanosoma cruzi

Cofactor

Cofactor Comment Organism Structure
FMN
-
Trypanosoma cruzi