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Literature summary for 1.3.3.3 extracted from

  • Modis, K.; Ramanujam, V.; Govar, A.; Lopez, E.; Anderson, K.; Wang, R.; Szabo, C.
    Cystathionine-gamma-lyase (CSE) deficiency increases erythropoiesis and promotes mitochondrial electron transport via the upregulation of coproporphyrinogen III oxidase and consequent stimulation of heme biosynthesis (2019), Biochem. Pharmacol., 169, 113604 .
    View publication on PubMed
Search for more literature for 1.3.3.3

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Mus musculus 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
coproporphyrinogen III + O2 + 2 H+ Mus musculus
-
 protoporphyrinogen-IX + 2 CO2 + 2 H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
coproporphyrinogen III + O2 + 2 H+
-
 Mus musculus protoporphyrinogen-IX + 2 CO2 + 2 H2O
-
 ?

Synonyms

Synonyms Comment Organism
coproporphyrinogen III oxidase
-
 Mus musculus
CPOX
-
 Mus musculus

Expression

Organism Comment Expression
Mus musculus addition of NaHS suppresses enzyme promoter activity down
Mus musculus cystathionine gamma-lyase deficient mice exhibit elevated enzyme expression in the liver up

General Information

General Information Comment Organism
metabolism the enzyme is required for heme biosynthesis Mus musculus