BRENDA - Enzyme Database
show all sequences of 1.3.3.12

Studies on the sulfhydryl group of L-galactonolactone oxidase

Noguchi, E.; Nishikimi, M.; Yagi, K.; J. Biochem. 90, 33-38 (1981)

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
2,2'-dipyridyl disulfide
-
Saccharomyces cerevisiae
4,4'-dipyridyl disulfide
-
Saccharomyces cerevisiae
5,5'-dithiobis(2-nitrobenzoate)
-
Saccharomyces cerevisiae
HgCl2
-
Saccharomyces cerevisiae
iodoacetamide
-
Saccharomyces cerevisiae
N-ethylmaleimide
-
Saccharomyces cerevisiae
PCMB
-
Saccharomyces cerevisiae
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
L-galactono-1,4-lactone + O2
Saccharomyces cerevisiae
-
L-ascorbate + H2O2
-
-
-
Organism
Organism
UniProt
Commentary
Textmining
Saccharomyces cerevisiae
-
-
-
Purification (Commentary)
Purification (Commentary)
Organism
-
Saccharomyces cerevisiae
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
L-galactono-1,4-lactone + O2
-
389745
Saccharomyces cerevisiae
L-ascorbate + H2O2
-
-
-
-
L-galactono-1,4-lactone + O2
-
389745
Saccharomyces cerevisiae
L-ascorbate + H2O2
-
389745
Saccharomyces cerevisiae
?
Cofactor
Cofactor
Commentary
Organism
Structure
FAD
enzyme contains a covalently bound flavin
Saccharomyces cerevisiae
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
FAD
enzyme contains a covalently bound flavin
Saccharomyces cerevisiae
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
2,2'-dipyridyl disulfide
-
Saccharomyces cerevisiae
4,4'-dipyridyl disulfide
-
Saccharomyces cerevisiae
5,5'-dithiobis(2-nitrobenzoate)
-
Saccharomyces cerevisiae
HgCl2
-
Saccharomyces cerevisiae
iodoacetamide
-
Saccharomyces cerevisiae
N-ethylmaleimide
-
Saccharomyces cerevisiae
PCMB
-
Saccharomyces cerevisiae
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
L-galactono-1,4-lactone + O2
Saccharomyces cerevisiae
-
L-ascorbate + H2O2
-
-
-
Purification (Commentary) (protein specific)
Commentary
Organism
-
Saccharomyces cerevisiae
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
L-galactono-1,4-lactone + O2
-
389745
Saccharomyces cerevisiae
L-ascorbate + H2O2
-
-
-
-
L-galactono-1,4-lactone + O2
-
389745
Saccharomyces cerevisiae
L-ascorbate + H2O2
-
389745
Saccharomyces cerevisiae
?
Other publictions for EC 1.3.3.12
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
724431
Kudryashova
Galactonolactone oxidoreductas ...
Trypanosoma cruzi, Trypanosoma cruzi X10/6
Biochim. Biophys. Acta
1814
545-552
2011
-
1
1
-
1
-
-
-
-
-
-
2
-
6
-
-
1
-
1
-
1
-
10
1
2
-
-
-
-
2
-
-
1
-
-
-
-
1
1
1
-
1
-
-
-
-
-
-
-
-
2
-
-
-
1
1
-
1
-
10
1
-
-
-
-
2
-
-
-
-
2
2
-
-
-
684985
Logan
The terminal step in vitamin C ...
Trypanosoma cruzi
Biochem. J.
407
419-426
2007
-
-
1
-
6
-
4
2
-
-
1
-
-
5
-
-
1
-
-
2
-
-
2
-
2
-
-
1
2
1
-
-
1
-
-
-
-
-
1
1
-
6
-
-
4
-
2
-
-
1
-
-
-
-
1
-
2
-
-
2
-
-
-
1
2
1
-
-
-
-
-
-
-
-
-
389748
Nishikimi
-
Identification by bacterial ex ...
Saccharomyces cerevisiae
Biochem. Mol. Biol. Int.
44
907-913
1998
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
389749
De Gara
-
The biogenesis of galactone-ga ...
Avena sativa
Phytochemistry
31
755-756
1992
-
-
-
-
-
-
1
-
1
-
-
1
-
1
-
-
-
-
-
-
-
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
1
-
-
-
-
-
-
-
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
389744
Bleeg
Biosynthesis of ascorbate in y ...
Saccharomyces cerevisiae
Eur. J. Biochem.
127
391-396
1982
-
-
-
-
-
-
7
6
1
1
3
1
-
2
-
-
1
-
-
-
1
1
6
1
-
-
-
-
-
1
-
-
1
2
-
-
-
-
-
1
-
-
-
-
7
2
6
1
1
3
1
-
-
-
1
-
-
1
1
6
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
389745
Noguchi
Studies on the sulfhydryl grou ...
Saccharomyces cerevisiae
J. Biochem.
90
33-38
1981
-
-
-
-
-
-
7
-
-
-
-
1
-
1
-
-
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
7
-
-
-
-
-
1
-
-
-
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
389746
Kenney
Identification of the covalent ...
Saccharomyces cerevisiae
FEBS Lett.
97
40-42
1979
-
-
-
-
-
-
-
-
-
-
-
1
-
2
-
-
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
389747
Nishikimi
Occurrence in yeast of L-galac ...
Saccharomyces cerevisiae
Arch. Biochem. Biophys.
191
479-486
1978
-
-
-
-
-
-
1
-
1
-
2
1
-
3
-
-
1
-
-
-
1
-
4
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
1
-
-
1
-
2
1
-
-
-
1
-
-
1
-
4
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-