Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Plasmodium falciparum |
Crystallization (Comment) | Organism |
---|---|
as binary complex with NADH and as ternary complex with NAD+ and triclosan, crystals diffract to 2.5 A and 2.2 A, respectively | Plasmodium falciparum |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
triclosan | increase in inhibition in the presence of NAD+ due to the movement of the substrate-binding loop | Plasmodium falciparum |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Plasmodium falciparum | - |
- |
- |
Purification (Comment) | Organism |
---|---|
recombinant PfENR | Plasmodium falciparum |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
trans-but-2-enoyl-CoA + NADH | - |
Plasmodium falciparum | butanoyl-CoA + NAD+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
pfENR | - |
Plasmodium falciparum |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | - |
Plasmodium falciparum |