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Literature summary for 1.3.1.8 extracted from

  • Strom, K.A.; Galeos, W.L.; Davidson, L.A.; Kumar, S.
    Enoyl coenzyme A reduction by bovine mammary fatty acid synthetase. Specificity and other characteristics (1979), J. Biol. Chem., 254, 8153-8158.
    View publication on PubMed
Search for more literature for 1.3.1.8

General Stability

General Stability Organism
fatty acid synthetase with enoyl-CoA reductase activity: denaturation by mechanical agitation, exposure to air, uneven surfaces such as scratched glass, membranes for ultrafiltration Bos taurus

Inhibitors

Inhibitors Comment Organism Structure
butyryl-CoA
-
 Bos taurus
NADP+
-
 Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Oxidation Stability

Oxidation Stability Organism
denaturation by exposure to air Bos taurus

Purification (Commentary)

Purification (Comment) Organism
fatty acid synthetase, also exhibiting crotonyl-CoA reductase activity Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
mammary gland
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1
-
-
 Bos taurus

Storage Stability

Storage Stability Organism
liquid N2, 30-50% loss of activity by thawing Bos taurus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-methyl-trans-crotonyl-CoA + NADPH 2% of trans-crotonyl-CoA activity Bos taurus 2-methylbutanoyl-CoA + NADP+
-
 ?
2-trans-dodecenoyl-CoA + NAD(P)H 15% of trans-crotonyl-CoA activity Bos taurus dodecanoyl-CoA + NAD(P)+
-
 ?
2-trans-hexadecenoyl-CoA + NADPH 13% of trans-crotonyl-CoA activity Bos taurus hexadecanoyl CoA + NADP+
-
 ?
2-trans-hexenoyl-CoA + NAD(P)H 30% of trans-crotonyl-CoA activity Bos taurus hexanoyl-CoA + NADP+
-
 ?
3-butenoyl-CoA + NADPH 7% of trans-crotonyl-CoA activity Bos taurus butanoyl-CoA + NADP+
-
 ?
3-methyl-crotonyl-CoA + NADPH 17% of trans-crotonyl-CoA activity Bos taurus 3-methylbutanoyl-CoA + NADP+
-
 ?
crotonyl-CoA + NAD(P)H cis-crotonyl-CoA 30% of trans-crotonyl-CoA activity Bos taurus butanoyl-CoA + NADP+
-
 ?
additional information no reduction of trans-crotonyl-S-pantetheine Bos taurus ?
-
 ?

Cofactor

Cofactor Comment Organism Structure
NADPH inactive with NADH Bos taurus