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Literature summary for 1.3.1.38 extracted from
- A novel cytosolic isoform of mitochondrial trans-2-enoyl-CoA reductase enhances peroxisome proliferator-activated receptor alpha activity (2014), Endocrinol. Metab. (Seoul), 29, 185-194.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in HeLa cells | Rattus norvegicus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Rattus norvegicus | 5829 | - |
| mitochondrion | - |
Rattus norvegicus | 5739 | - |
| nucleus | - |
Rattus norvegicus | 5634 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| trans-2,3-dehydroacyl-CoA + NADPH + H+ | Rattus norvegicus | - |
acyl-CoA + NADP+ | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | the enzyme directly binds with and enhances peroxisome proliferator-activated receptor alpha activity | Rattus norvegicus | ? | - |
? | |
| trans-2,3-dehydroacyl-CoA + NADPH + H+ | - |
Rattus norvegicus | acyl-CoA + NADP+ | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| MECR | - |
Rattus norvegicus |
| trans-2-enoyl-CoA reductase (NADPH) | - |
Rattus norvegicus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADPH | - |
Rattus norvegicus | |
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Release 2023.1 (January 2023)
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