Literature summary for 1.3.1.34 extracted from

Mizugaki, M.; Nishimaki, T.; Yamamoto, H.; Nishimura, S.; Sagi, M.; Yamanaka, H.
Studies on the metabolism of unsaturated fatty acids. VIII. Induction of 2,4-dienoyl-CoA reductase in Escherichia coli on the addition of unsaturated fatty acids (1982), J. Biochem., 91, 1453-1456.

Search for more literature for 1.3.1.34

Inhibitors

Inhibitors	Comment	Organism	Structure
iodoacetic acid	inhibition of 70-80% at concentration of 1 mM	Escherichia coli
N-ethylmaleimide	inhibition of 70-80% at concentration of 1 mM	Escherichia coli

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-
Escherichia coli B / ATCC 11303	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
gel filtration	Escherichia coli

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2-trans,4-trans-hexadienoyl-CoA + NADPH	-	Escherichia coli	?	-	ir
2-trans,4-trans-hexadienoyl-CoA + NADPH	-	Escherichia coli B / ATCC 11303	?	-	ir

Synonyms

Synonyms	Comment	Organism
2,4-dienoyl-CoA reductase	-	Escherichia coli

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
7.4	-	trans,trans-2,4-hexadienoyl-CoA + NADPH	Escherichia coli

pH Stability

pH Stability	pH Stability Maximum	Comment	Organism
6	7.5	stable at 40°C for 10 min	Escherichia coli
8	-	activity loss about 50%	Escherichia coli
9	-	total loss of activity	Escherichia coli

Cofactor

Cofactor	Comment	Organism	Structure
NADPH	not NADH	Escherichia coli

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)