Literature summary for 1.3.1.24 extracted from

Kim, S.J.; Shin, M.J.; Kim, D.W.; Yeo, H.J.; Yeo, E.J.; Choi, Y.J.; Sohn, E.J.; Han, K.H.; Park, J.; Lee, K.W.; Park, J.K.; Cho, Y.J.; Kim, D.S.; Eum, W.S.; Choi, S.Y.
Tat-Biliverdin reductase A exerts a protective role in oxidative stress-induced hippocampal neuronal cell damage by regulating the apoptosis and MAPK signaling (2020), Int. J. Mol. Sci., 21, 2672 .

Search for more literature for 1.3.1.24

Application

Application	Comment	Organism
pharmacology	transduced fusion protein Tat-biliverdin reductase A (Tat-BLVRA) markedly inhibits cell death, DNA fragmentation, and generation of ROS. Transduced Tat-BLVRA inhibits the apoptosis and mitogen activated protein kinase (MAPK) signaling pathway and it passes through the blood-brain barrier (BBB) and significantly prevents hippocampal cell death in an ischemic model. Tat-BLVRA provides a possibility as a therapeutic molecule for ischemia	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	Q9CY64	-	-

Purification (Commentary)

Purification (Comment)	Organism
transduced fusion protein Tat-biliverdin reductase A (Tat-BLVRA)	Mus musculus

Source Tissue

Source Tissue	Comment	Organism	Textmining
HT-22 cell	fusion protein Tat-biliverdin reductase A (Tat-BLVRA) is effiently transduced into HT-22 cells	Mus musculus	-

Synonyms

Synonyms	Comment	Organism
biliverdin reductase A	-	Mus musculus
BLVRA	-	Mus musculus

General Information

General Information	Comment	Organism
physiological function	the enzyme exerts a protective role in oxidative stress-induced hippocampal neuronal cell damage by regulating the apoptosis and MAPK signaling	Mus musculus

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Release 2023.1 (January 2023)