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Literature summary for 1.3.1.24 extracted from

  • Spencer, A.L.; Bagai, I.; Becker, D.F.; Zuiderweg, E.R.; Ragsdale, S.W.
    Protein/protein interactions in the mammalian heme degradation pathway: heme oxygenase-2, cytochrome P450 reductase, and biliverdin reductase (2014), J. Biol. Chem., 289, 29836-29858.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3)-RIL cells Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
33000
-
x * 33000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
biliverdin + NADH + H+ Homo sapiens
-
bilirubin + NAD+
-
r
biliverdin + NADPH + H+ Homo sapiens
-
bilirubin + NADP+
-
r

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
glutathione-Sepharose column chromatography, and Superdex 200 gel filtration Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
biliverdin + NADH + H+
-
Homo sapiens bilirubin + NAD+
-
r
biliverdin + NADPH + H+
-
Homo sapiens bilirubin + NADP+
-
r

Subunits

Subunits Comment Organism
? x * 33000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
BVR
-
Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NADH
-
Homo sapiens
NADPH
-
Homo sapiens