Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | in normoxic cells, hBVR is located primarily in the cytoplasm, with some protein also being seen in the nucleus | Homo sapiens | 5737 | - |
nucleus | hBVR is detected in the nucleus at 1, 2, and 4 h after hypoxia, at which times its kinase and reductase activities are increased | Homo sapiens | 5634 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
hypoxia activates hBVR activity | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
biliverdin reductase | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | hypoxia positively regulates hBVR promoter | up |
Homo sapiens | overexpression of IkappaB increases hBVR mRNA | up |
Homo sapiens | TNF-alpha negatively regulates hBVR promoter | up |