Inhibitors | Comment | Organism | Structure |
---|---|---|---|
finasteride | replacement of residues 26-29 (AVFA) from isozyme 1 with residues 21-24 (GALA) from isozyme 2 increases the resistance to finasteride, what confirms that residues 26-29 from isozyme 1 are involved in the inhibitor/substrate binding but suggest residues 21-29 from isozyme 2 are not. More findings indicate that residues 15-17 of human 5 alpha-reductase 2 participate in inhibitor/substrate binding | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |