Inhibitors | Comment | Organism | Structure |
---|---|---|---|
17beta-Carbamoyl-1,3,5(10)-estratriene-3-carboxylic acids | formation of enzyme-NADP+-inhibitor complex | Homo sapiens | |
17beta-Carbamoyl-1,3,5(10)-estratriene-3-carboxylic acids | formation of enzyme-NADP+-inhibitor complex | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
a 3-oxo-5alpha-steroid + NADP+ = a 3-oxo-DELTA4-steroid + NADPH + H+ | mechanism | Homo sapiens | |
a 3-oxo-5alpha-steroid + NADP+ = a 3-oxo-DELTA4-steroid + NADPH + H+ | mechanism | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
prostate gland | - |
Homo sapiens | - |
prostate gland | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
progesterone + NADPH + H+ | - |
Homo sapiens | 5alpha-pregnan-3-20-dione + NADP+ | - |
? | |
progesterone + NADPH + H+ | - |
Rattus norvegicus | 5alpha-pregnan-3-20-dione + NADP+ | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Homo sapiens | |
NADPH | - |
Rattus norvegicus |