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Literature summary for 1.3.1.21 extracted from

  • Srikantaiah, M.V.; Assef, S.; Morin, R.J.
    Effects of Tween 80 on liver microsomal 7-dehydrocholesterol reductase (1978), Biochem. Biophys. Res. Commun., 81, 1087-1090.
    View publication on PubMed
Search for more literature for 1.3.1.21

Activating Compound

Activating Compound Comment Organism Structure
Sterol carrier protein from cytosol, required for activity, probably identical with lipid transfer protein Rattus norvegicus
Tween 80 can substitute carrier protein Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome cytosolic sterol carrier protein required for activity Rattus norvegicus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cholesta-5,7-dien-3-beta-ol + NADPH Rattus norvegicus
-
 cholesterol + NADP+
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cholesta-5,7-dien-3-beta-ol + NADPH
-
 Rattus norvegicus cholesterol + NADP+
-
 ?
cholesta-5,7-dien-3alpha-ol + NADPH i.e. 7-dehydroepicholesterol, 25% activity of that with 7-dehydrocholesterol Rattus norvegicus epicholesterol + NADP+
-
 ?
cholesta-5,7-dien-3beta-ol + NADPH
-
 Rattus norvegicus cholesterol + NADP+
-
 ?