Literature summary for 1.3.1.121 extracted from

He, J.; Magarvey, N.; Piraee, M.; Vining, L.
The gene cluster for chloramphenicol biosynthesis in Streptomyces venezuelae ISP5230 includes novel shikimate pathway homologues and a monomodular non-ribosomal peptide synthetase gene (2001), Microbiology, 147, 2817-2829 .

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
4-amino-4-deoxyprephenate + NAD+	Streptomyces venezuelae	-	3-(4-aminophenyl)pyruvate + CO2 + NADH + H+	-	?
4-amino-4-deoxyprephenate + NAD+	Streptomyces venezuelae ISP5230	-	3-(4-aminophenyl)pyruvate + CO2 + NADH + H+	-	?

Organism

Organism	UniProt	Comment	Textmining
Streptomyces venezuelae	-	-	-
Streptomyces venezuelae ISP5230	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4-amino-4-deoxyprephenate + NAD+	-	Streptomyces venezuelae	3-(4-aminophenyl)pyruvate + CO2 + NADH + H+	-	?
4-amino-4-deoxyprephenate + NAD+	-	Streptomyces venezuelae ISP5230	3-(4-aminophenyl)pyruvate + CO2 + NADH + H+	-	?

Synonyms

Synonyms	Comment	Organism
cmlC	-	Streptomyces venezuelae
cyclohexenyl dehydrogenase	-	Streptomyces venezuelae

Cofactor

Cofactor	Comment	Organism	Structure
NAD+	-	Streptomyces venezuelae

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Release 2023.1 (January 2023)