Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-hexadecynoyl-CoA | - |
Mycobacterium tuberculosis | |
2-octadecynoyl-CoA | - |
Mycobacterium tuberculosis | |
isoniazid | acts on the mycobacterial cell wall by preventing the FAS-II system from producing long-chain fatty acid precursors for mycolic acid biosynthesis | Mycobacterium tuberculosis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | - |
- |
- |
Mycobacterium tuberculosis mc(2)155 | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
2-trans-enoyl-acyl carrier protein reductase | - |
Mycobacterium tuberculosis |
InhA | - |
Mycobacterium tuberculosis |
General Information | Comment | Organism |
---|---|---|
metabolism | InhA belongs to the FAS-II system and participates in the mycolic acid pathway. The long-chain fatty acids produced by the FAS-II system serve as precursors for the formation of the meromycolic acids, which represent the C40-C60 main chain of mycolic acids | Mycobacterium tuberculosis |