BRENDA - Enzyme Database
show all sequences of 1.3.1.101

Stereochemistry of reduction in digeranylgeranylglycerophospholipid reductase involved in the biosynthesis of archaeal membrane lipids from Thermoplasma acidophilum

Nishimura, Y.; Eguchi, T.; Bioorg. Chem. 35, 276-283 (2007)

Data extracted from this reference:

Cloned(Commentary)
Cloned (Commentary)
Organism
expression in Escherichia coli Rosetta (DE3)
Thermoplasma acidophilum
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
43000
-
x * 43000, SDS-PAGE
Thermoplasma acidophilum
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate + 8 NAD(P)H + 8 H+
Thermoplasma acidophilum
formation of 2,3-di-O-phytanylglyceryl phosphate, which is the basic core structure of archaeal membrane lipids
2,3-bis-O-phytanyl-sn-glycerol 1-phosphate + 8 NAD(P)+
-
-
?
Organism
Organism
UniProt
Commentary
Textmining
Thermoplasma acidophilum
Q9HKS9
-
-
Purification (Commentary)
Purification (Commentary)
Organism
-
Thermoplasma acidophilum
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate + 8 NAD(P)H + 8 H+
-
719041
Thermoplasma acidophilum
2,3-bis-O-phytanyl-sn-glycerol 1-phosphate + 8 NAD(P)+
-
-
-
?
2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate + 8 NAD(P)H + 8 H+
formation of 2,3-di-O-phytanylglyceryl phosphate, which is the basic core structure of archaeal membrane lipids
719041
Thermoplasma acidophilum
2,3-bis-O-phytanyl-sn-glycerol 1-phosphate + 8 NAD(P)+
-
-
-
?
Subunits
Subunits
Commentary
Organism
?
x * 43000, SDS-PAGE
Thermoplasma acidophilum
Synonyms
Synonyms
Commentary
Organism
DGGGPL reductase
-
Thermoplasma acidophilum
Ta0516m
-
Thermoplasma acidophilum
Cofactor
Cofactor
Commentary
Organism
Structure
FAD
the cofactor is bound to the enzyme in the ratio 1:1
Thermoplasma acidophilum
Cloned(Commentary) (protein specific)
Commentary
Organism
expression in Escherichia coli Rosetta (DE3)
Thermoplasma acidophilum
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
FAD
the cofactor is bound to the enzyme in the ratio 1:1
Thermoplasma acidophilum
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
43000
-
x * 43000, SDS-PAGE
Thermoplasma acidophilum
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate + 8 NAD(P)H + 8 H+
Thermoplasma acidophilum
formation of 2,3-di-O-phytanylglyceryl phosphate, which is the basic core structure of archaeal membrane lipids
2,3-bis-O-phytanyl-sn-glycerol 1-phosphate + 8 NAD(P)+
-
-
?
Purification (Commentary) (protein specific)
Commentary
Organism
-
Thermoplasma acidophilum
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate + 8 NAD(P)H + 8 H+
-
719041
Thermoplasma acidophilum
2,3-bis-O-phytanyl-sn-glycerol 1-phosphate + 8 NAD(P)+
-
-
-
?
2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate + 8 NAD(P)H + 8 H+
formation of 2,3-di-O-phytanylglyceryl phosphate, which is the basic core structure of archaeal membrane lipids
719041
Thermoplasma acidophilum
2,3-bis-O-phytanyl-sn-glycerol 1-phosphate + 8 NAD(P)+
-
-
-
?
Subunits (protein specific)
Subunits
Commentary
Organism
?
x * 43000, SDS-PAGE
Thermoplasma acidophilum
Other publictions for EC 1.3.1.101
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
712772
Xu
Insights into substrate specif ...
Thermoplasma acidophilum
J. Mol. Biol.
404
403-417
2010
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1
1
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1
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6
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1
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1
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2
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1
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1
1
1
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1
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1
-
-
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-
1
-
-
-
-
-
-
-
-
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-
1
1
-
-
-
719041
Nishimura
Stereochemistry of reduction i ...
Thermoplasma acidophilum
Bioorg. Chem.
35
276-283
2007
-
-
1
-
-
-
-
-
1
-
1
1
-
2
-
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1
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-
-
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2
1
2
-
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-
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1
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-
1
1
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-
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1
-
1
1
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1
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2
1
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719758
Nishimura
Biosynthesis of archaeal membr ...
Thermoplasma acidophilum
J. Biochem.
139
1073-1081
2006
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1
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3
1
1
1
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3
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1
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1
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6
1
1
1
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1
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2
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2
-
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-
1
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3
1
1
1
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1
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1
-
6
1
1
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-
1
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