Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aspergillus fumigatus | - |
- |
- |
Aspergillus fumigatus FGSC A1141 | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
EasA | - |
Aspergillus fumigatus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | - |
Aspergillus fumigatus |
General Information | Comment | Organism |
---|---|---|
malfunction | disruption of the easA gene leads to accumulation of chanoclavine-I and chanoclavine-I-aldehyde | Aspergillus fumigatus |
metabolism | the enzyme is required for incorporation of chanoclavine-I-aldehyde into more-complex ergot alkaloids, presumably by reducing the double bond conjugated to the aldehyde group, thus facilitating ring closure | Aspergillus fumigatus |