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Literature summary for 1.3.1.1 extracted from

  • Ishikawa, M.; Miyauchi, T.; Kashiwagi, Y.
    Clinical implications of thymidylate synthetase, dihydropyrimidine dehydrogenase and orotate phosphoribosyl transferase activity levels in colorectal carcinoma following radical resection and administration of adjuvant 5-FU chemotherapy (2008), BMC Cancer, 8, 188.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
colorectal adenocarcinoma cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5-fluorouracil + NADH + H+
-
Homo sapiens 5-fluoro-5,6-dihydrouracil + NAD+
-
?

Synonyms

Synonyms Comment Organism
dihydropyrimidine dehydrogenase
-
Homo sapiens
DPD
-
Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Homo sapiens