Literature summary for 1.21.99.4 extracted from

Curcio-Morelli, C.; Gereben, B.; Zavacki, A.M.; Kim, B.W.; Huang, S.; Harney, J.W.; Larsen, P.R.; Bianco, A.C.
In vivo dimerization of types 1, 2, and 3 iodothyronine selenodeiodinases (2003), Endocrinology, 144, 937-946.

Search for more literature for 1.21.99.4

Cloned(Commentary)

Cloned (Comment)	Organism
expression in HEK-293 cells	Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
55000	-	x * 55000, SDS-PAGE, overexpressed enzyme can homodimerize probably through disulfide bridges. Monomeric form is also catalytically active	Homo sapiens
62000	-	x * 62000, SDS-PAGE, overexpressed enzyme can homodimerize probably through disulfide bridges. Monomeric form is also catalytically active	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P49895	-	-
Homo sapiens	P49895	tye I enzyme DIO1	-
Homo sapiens	Q92813	-	-
Homo sapiens	Q92813	tye II enzyme DIO2	-

Subunits

Subunits	Comment	Organism
dimer	overexpressed enzyme can homodimerize probably through disulfide bridges, type 1 iodothyronine selenodeiodinase	Homo sapiens
dimer	overexpressed enzyme can homodimerize probably through disulfide bridges, type 2 iodothyronine selenodeiodinase	Homo sapiens
dimer	x * 55000, SDS-PAGE, overexpressed enzyme can homodimerize probably through disulfide bridges. Monomeric form is also catalytically active	Homo sapiens
dimer	x * 62000, SDS-PAGE, overexpressed enzyme can homodimerize probably through disulfide bridges. Monomeric form is also catalytically active	Homo sapiens

Synonyms

Synonyms	Comment	Organism
DIO1	-	Homo sapiens
DIO2	-	Homo sapiens
types 1 iodothyronine selenodeiodinase	-	Homo sapiens
types 2 iodothyronine selenodeiodinase	-	Homo sapiens

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Release 2023.1 (January 2023)