Organism | UniProt | Comment | Textmining |
---|---|---|---|
Clostridioides difficile | Q185M6 | selenium-containing subunit GrdA | - |
Clostridioides difficile 630 | Q185M6 | selenium-containing subunit GrdA | - |
Synonyms | Comment | Organism |
---|---|---|
GrdA | - |
Clostridioides difficile |
Organism | Comment | Expression |
---|---|---|
Clostridioides difficile | presence of proline inhibits transcription of the grd operon encoding glycine reductase. Protein PrdR negatively regulates transcription of the glycine reductase-encoding genes in the presence of proline | up |
General Information | Comment | Organism |
---|---|---|
physiological function | growth rate of a subunit GrdA gene deletion strains is similar to that of the wild-type. Intracellular proline concentrations depend on the activity of proline reductase but not on the activity of glycine reductase. Subunit grdE levels in in a subunit GrdA mutant are 10fold higher than in wild-type cells and12fold more abundant in glycine-supplemented medium. Induction of grdE expression in the presence of glycine is notably higher in the grdA mutant than in the wild-type strain | Clostridioides difficile |