Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli W3110 cells | Arabidopsis thaliana |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
arsenite + acceptor | Arabidopsis thaliana | - |
arsenate + reduced acceptor | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
root | - |
Arabidopsis thaliana | - |
shoot | - |
Arabidopsis thaliana | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
arsenite + acceptor | - |
Arabidopsis thaliana | arsenate + reduced acceptor | - |
? |
Synonyms | Comment | Organism |
---|---|---|
HAC1 | - |
Arabidopsis thaliana |
Organism | Comment | Expression |
---|---|---|
Arabidopsis thaliana | enzyme expression is induced by arsenate | up |
General Information | Comment | Organism |
---|---|---|
malfunction | plants lacking the enzyme lose their ability to efflux arsenite from roots, leading to both increased transport of arsenic into the central vascular tissue and on into the shoot. Loss of enzyme-encoded arsenic reduction leads to a significant increase in arsenic accumulation in shoots, causing an increased sensitivity to arsenate toxicity | Arabidopsis thaliana |
physiological function | the enzyme functions to reduce arsenate to arsenite in the outer cell layer of the root, facilitating efflux of arsenic as arsenite back into the soil to limit both its accumulation in the root and transport to the shoot. Arsenate reduction by the enzyme in the pericycle may play a role in limiting arsenic loading into the xylem | Arabidopsis thaliana |