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Literature summary for 1.2.7.4 extracted from

  • Lindahl, P.A.
    Implications of a carboxylate-bound C-cluster structure of carbon monoxide dehydrogenase (2008), Angew. Chem., 47, 4054-4056.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
S2- partial inhibitor Carboxydothermus hydrogenoformans
S2- partial inhibitor Moorella thermoacetica
S2- partial inhibitor Rhodospirillum rubrum

Metals/Ions

Metals/Ions Comment Organism Structure
Fe2+ contains a NiFe center, called C-cluster Moorella thermoacetica
Fe2+ contains a NiFe center, called C-cluster Rhodospirillum rubrum
Fe2+ contains a NiFe center, called C-cluster Carboxydothermus hydrogenoformans
Ni2+ contains a NiFe center, called C-cluster Moorella thermoacetica
Ni2+ contains a NiFe center, called C-cluster Rhodospirillum rubrum
Ni2+ contains a NiFe center, called C-cluster Carboxydothermus hydrogenoformans

Organism

Organism UniProt Comment Textmining
Carboxydothermus hydrogenoformans
-
-
-
Moorella thermoacetica
-
-
-
Rhodospirillum rubrum
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CO + H2O + acceptor
-
Moorella thermoacetica CO2 + reduced acceptor
-
r
CO + H2O + acceptor
-
Rhodospirillum rubrum CO2 + reduced acceptor
-
r
CO + H2O + acceptor
-
Carboxydothermus hydrogenoformans CO2 + reduced acceptor
-
r

Subunits

Subunits Comment Organism
homodimer
-
Moorella thermoacetica
homodimer
-
Rhodospirillum rubrum
homodimer
-
Carboxydothermus hydrogenoformans

Synonyms

Synonyms Comment Organism
ACS/CODH bifunctional enzyme with ACS alpha subunits and CODH beta subunits Moorella thermoacetica
CODH
-
Rhodospirillum rubrum
CODH
-
Carboxydothermus hydrogenoformans