Literature summary for 1.2.7.4 extracted from

Feng, J.; Lindahl, P.A.
Effect of sodium sulfide on Ni-containing carbon monoxide dehydrogenases (2004), J. Am. Chem. Soc., 126, 9094-9100.

Search for more literature for 1.2.7.4

Inhibitors

Inhibitors	Comment	Organism	Structure
Sulfide	partial	Moorella thermoacetica
Sulfide	partial	Rhodospirillum rubrum

Organism

Organism	UniProt	Comment	Textmining
Moorella thermoacetica	-	-	-
Rhodospirillum rubrum	-	-	-

Reaction

Reaction	Comment	Organism	Reaction ID
CO + H2O + 2 oxidized ferredoxin = CO2 + 2 reduced ferredoxin + 2 H+	mechanism, CO binding labilizes the hydroxyl bridging Ni and Fe and increases the nucleophilic tendency toward attacking Ni-bound carbonyl	Moorella thermoacetica	a
CO + H2O + 2 oxidized ferredoxin = CO2 + 2 reduced ferredoxin + 2 H+	mechanism, CO binding labilizes the hydroxyl bridging Ni and Fe and increases the nucleophilic tendency toward attacking Ni-bound carbonyl	Rhodospirillum rubrum	a

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.00004	-	Sulfide	pH 7.5, 30°C	Rhodospirillum rubrum
0.00006	-	Sulfide	pH 7.5, 30°C	Moorella thermoacetica

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Release 2023.1 (January 2023)