Activating Compound | Comment | Organism | Structure |
---|---|---|---|
thiamine diphosphate | - |
Bos taurus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-(2-Thienyl)-2-oxo-3-butenoate | - |
Bos taurus | |
4-(3-Thienyl)-2-oxo-3-butenoate | non-competitive | Bos taurus | |
cinnamylpyruvate | non-competitive | Bos taurus | |
Furfurylidenepyruvate | competitive | Bos taurus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00067 | - |
3-methyl-2-oxobutanoate | - |
Bos taurus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-methyl-2-oxobutanoate + [dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine | - |
Bos taurus | [dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine + CO2 | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
CoA | - |
Bos taurus | |
NAD+ | - |
Bos taurus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0005 | - |
Furfurylidenepyruvate | - |
Bos taurus | |
0.15 | - |
4-(3-Thienyl)-2-oxo-3-butenoate | - |
Bos taurus | |
0.5 | - |
cinnamylpyruvate | - |
Bos taurus |