Literature summary for 1.2.4.2 extracted from

Bunik, V.; Kaehne, T.; Degtyarev, D.; Shcherbakova, T.; Reiser, G.
Novel isoenzyme of 2-oxoglutarate dehydrogenase is identified in brain, but not in heart (2008), FEBS J., 275, 4990-5006.

Search for more literature for 1.2.4.2

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrion	-	Rattus norvegicus	5739	-

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
117400	-	calculated from amino acid sequence	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
poly(ethylene glycol) fractionation and Sephacryl HR300 gel filtration	Rattus norvegicus

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	isozyme 2-oxoglutarate dehydrogenase-like protein	Rattus norvegicus	-
additional information	2-oxoglutarate dehydrogenase-like protein is not detected in heart	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2-oxoglutarate + [dihydrolipoyllysine-residue succinyltransferase] lipoyllysine	-	Rattus norvegicus	[dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + CO2	-	?

Synonyms

Synonyms	Comment	Organism
2-oxoglutarate dehydrogenase	first and rate-limiting component of the multienzyme 2-oxoglutarate dehydrogenase complex	Rattus norvegicus
2-oxoglutarate dehydrogenase-like protein	brain-specific isozyme	Rattus norvegicus
E1o	-	Rattus norvegicus
OGDH	-	Rattus norvegicus
OGDHL	brain-specific isozyme	Rattus norvegicus

Cofactor

Cofactor	Comment	Organism	Structure
NAD+	-	Rattus norvegicus
thiamine diphosphate	-	Rattus norvegicus

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Release 2023.1 (January 2023)