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Literature summary for 1.2.3.6 extracted from
- Pyruvate oxidase (CoA acetylating) in Entamoeba histolytica (1975), Biochem. Biophys. Res. Commun., 65, 591-596.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | activity is not enhanced by phosphatidyl-choline, -inositol, and -ethanolamine or by artificial electron acceptors | Entamoeba histolytica |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Entamoeba histolytica | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| ammonium sulfate, hydroxyapatite, partially purified | Entamoeba histolytica |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| pyruvate + CoA + O2 = acetyl-CoA + CO2 + H2O2 | enzyme catalyzes transacetylation from pyruvate to CoA by an oxidase reaction in which H2O2 is produced | Entamoeba histolytica |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 2.1 | - |
- |
Entamoeba histolytica |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| pyruvate + CoA + O2 | - |
Entamoeba histolytica | acetyl-CoA + CO2 + H2O2 | - |
? |  |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| FAD | - |
Entamoeba histolytica | |
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Release 2023.1 (January 2023)
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