Literature summary for 1.2.3.15 extracted from

  • Whittaker, M.M.; Kersten P.J.; Nakamura, N.; Sanders-Loehr, J.; Schweizer, E.S.; Whittaker, J.W.
    Glyoxal oxidase from Phanerochaete chrysosporium is a new radical-copper oxidase (1996), J. Biol. Chem., 271, 681-687.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information purified native glyoxal oxidase is catalytically inactive, but can be oxidatively activated by lignin peroxidase molybdicyanide (K3Mo(CN)8) or hexachloroiridate (Na2IrCl6), or Mn3+ EDTA Phanerodontia chrysosporium

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Aspergillus nidulans Phanerodontia chrysosporium

Inhibitors

Inhibitors Comment Organism Structure
phosphate millimolar inhibitor Phanerodontia chrysosporium

Metals/Ions

Metals/Ions Comment Organism Structure
Cu2+ 0.7-0.8 equivalents of Cu2+ per mol enzyme Phanerodontia chrysosporium

Organism

Organism UniProt Comment Textmining
Phanerodontia chrysosporium Q01772
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
methylglyoxal + H2O + O2
-
Phanerodontia chrysosporium methylglyoxylate + H2O2
-
?

Synonyms

Synonyms Comment Organism
methylglyoxal oxidase
-
Phanerodontia chrysosporium

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
5.1
-
phosphate at pH 4.5, temperature not specified in the publication Phanerodontia chrysosporium
1
-
phosphate at pH 6.0, temperature not specified in the publication Phanerodontia chrysosporium