Organism | UniProt | Comment | Textmining |
---|---|---|---|
Staphylococcus aureus | A0A0H3KDU5 | - |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
4,4'-diaponeurosporen-4-al + NAD(P)+ = 4,4'-diaponeurosporenoic acid + NAD(P)H + H+ | broad substrate specificity, in addition catalyzes synthesis of 4,4'-diapolycopen-4'-al-4-oic acid and 4,4'-diapolycopenoic acid from the respective aldehydes | Staphylococcus aureus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4,4'-diapolycopen-4'-al-4-oic acid + NAD(P)+ | - |
Staphylococcus aureus | 4,4'-diapolycopen-4,4'-dioic acid + NAD(P)H + H+ | - |
? | |
4,4'-diapolycopen-4-al + NAD(P)+ | - |
Staphylococcus aureus | 4,4'-diapolycopenoic acid + NAD(P)H + H+ | - |
? | |
4,4'-diapolycopenedial + NAD(P)+ | - |
Staphylococcus aureus | 4,4'-diapolycopen-4'-al-4-oic acid + NAD(P)H + H+ | - |
? | |
4,4'-diaponeurosporen-4-al + NAD(P)+ | - |
Staphylococcus aureus | 4,4'-diaponeurosporenoic acid + NAD(P)H + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ALDH | - |
Staphylococcus aureus |
NWMN_2026 | - |
Staphylococcus aureus |
General Information | Comment | Organism |
---|---|---|
physiological function | final enzyme in the biosynthetic pathway for staphyloxanthin, a C30 carotenoid biosynthesized by Staphylococcus aureus. Deletion of the gene abolishes staphyloxanthin biosynthesis and causes accumulation of 4,4'-diaponeurosporen-4-al. When the complete staphyloxanthin biosynthetic pathway is expressed using an artificial synthetic operon in Escherichia coli, staphyloxanthin-like compounds, which contain altered fatty acid acyl chains, and novel carotenoid compounds aere produced, indicating functional expression and coordination of the six staphyloxanthin pathway enzymes | Staphylococcus aureus |