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Literature summary for 1.2.1.84 extracted from

  • Li, D.T.; Dai, Y.T.; Chen, X.; Wang, X.Q.; Li, Z.D.; Moussian, B.; Zhang, C.X.
    Ten fatty acyl-CoA reductase family genes were essential for the survival of the destructive rice pest, Nilaparvata lugens (2020), Pest Manag. Sci., 76, 2304-2315 .
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Nilaparvata lugens
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brown planthopper
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Source Tissue

Source Tissue Comment Organism Textmining
fat body
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Nilaparvata lugens
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gut highest expression of isoforms FAR5 and Far11 Nilaparvata lugens
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integument highest expression of isoforms FAR1, FAR2, FAR3, FAR7, FAR10, FAR13, FAR14 and FAR17 Nilaparvata lugens
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ovary highest expression of isoforms FAR4, FAR8, and FAR12 Nilaparvata lugens
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testis highest expression of isoforms FAR6, FAR9 and FAR15 Nilaparvata lugens
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Synonyms

Synonyms Comment Organism
FAR1 isoform Nilaparvata lugens
FAR10 isoform Nilaparvata lugens
FAR11 isoform Nilaparvata lugens
FAR12 isoform Nilaparvata lugens
FAR13 isoform Nilaparvata lugens
FAR14 isoform Nilaparvata lugens
FAR15 isoform Nilaparvata lugens
FAR16 isoform Nilaparvata lugens
FAR17 isoform Nilaparvata lugens
FAR2 isoform Nilaparvata lugens
FAR3 isoform Nilaparvata lugens
FAR4 isoform Nilaparvata lugens
FAR5 isoform Nilaparvata lugens
FAR6 isoform Nilaparvata lugens
FAR7 isoform Nilaparvata lugens
FAR8 isoform Nilaparvata lugens
FAR9 isoform Nilaparvata lugens
fatty acyl-CoA reductase
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Nilaparvata lugens

Cofactor

Cofactor Comment Organism Structure
NADPH
-
Nilaparvata lugens

General Information

General Information Comment Organism
malfunction knockdown of isoforms FAR5, 6, 11 or 15 is lethal and causes a slender body shape, while the old cuticles of the respective animals remain attached to the abdomen or failed to split open from the nota. Knockdown of isoform FAR9 results in a phenotype, with a smooth body surface and a decrease in cuticular hydrocarbon amounts. Knockdown of isoforms FAR1, 4, 5, 6, 8, 9, 11 and 13 additionally results in female adult infertility Nilaparvata lugens