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Literature summary for 1.2.1.70 extracted from

  • Nagai, S.; Koide, M.; Takahashi, S.; Kikuta, A.; Aono, M.; Sasaki-Sekimoto, Y.; Ohta, H.; Takamiya, K.; Masuda, T.
    Induction of isoforms of tetrapyrrole biosynthetic enzymes, AtHEMA2 and AtFC1, under stress conditions and their physiological functions in Arabidopsis (2007), Plant Physiol., 144, 1039-1051.
    View publication on PubMedView publication on EuropePMC
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Activating Compound

Activating Compound Comment Organism Structure
cycloheximide
-
 Arabidopsis thaliana
additional information is induced in photosynthetic tissues by oxidative stresses such as wounding Arabidopsis thaliana
Ozone induces expression in photosynthetic tissues Arabidopsis thaliana
puromycin
-
 Arabidopsis thaliana

Application

Application Comment Organism
additional information the tetrapyrrole biosynthetic pathway is controlled by HEMA2 and FC1, which normally functions for heme biosynthesis in nonphotosynthetic tissues, but is induced in photosynthetic tissues under oxidative conditions to supply heme for defensive hemoproteins outside plastids Arabidopsis thaliana

Protein Variants

Protein Variants Comment Organism
additional information insertional knockout mutants show heme contents of the roots about half of that of the wild-type and reduction of the ozone-induced increase in heme content Arabidopsis thaliana

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
seedling
-
 Arabidopsis thaliana
-

Synonyms

Synonyms Comment Organism
HEMA2
-
 Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Arabidopsis thaliana