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Literature summary for 1.2.1.7 extracted from

  • Kohler, A.; Broeg, K.; Bahns, S.
    Localization of a tumor-associated phenotype of benzaldehyde dehydrogenase in liver carcinogenesis of flounder by quantitative histochemistry (1998), Mar. Environ. Res., 46, 185-189.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
Disulfiram
-
Platichthys flesus
Disulfiram
-
Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
benzaldehyde + NADP+ + H2O Rattus norvegicus
-
benzoate + NADPH
-
?
benzaldehyde + NADP+ + H2O Platichthys flesus
-
benzoate + NADPH
-
?

Organism

Organism UniProt Comment Textmining
Platichthys flesus
-
flounder
-
Rattus norvegicus
-
-
-

Reaction

Reaction Comment Organism Reaction ID
benzaldehyde + NADP+ + H2O = benzoate + NADPH + H+ inducible by xenobiotics, like DDT and TCDD Rattus norvegicus
benzaldehyde + NADP+ + H2O = benzoate + NADPH + H+ inducible by xenobiotics, like DDT and TCDD Platichthys flesus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Platichthys flesus
-
liver early eosinophilic focus, basophilic adenoma and hepatocellular carcinom Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzaldehyde + NADP+ + H2O
-
Rattus norvegicus benzoate + NADPH
-
?
benzaldehyde + NADP+ + H2O
-
Platichthys flesus benzoate + NADPH
-
?

Cofactor

Cofactor Comment Organism Structure
NADP+
-
Rattus norvegicus
NADP+
-
Platichthys flesus