Activating Compound | Comment | Organism | Structure |
---|---|---|---|
ADP | does not act as cofactor, but has some stimulatory effect | Lithospermum erythrorhizon | |
AMP | does not act as cofactor, but has some stimulatory effect | Lithospermum erythrorhizon | |
ATP | does not act as cofactor, but has some stimulatory effect, can partly be replaced by ADP or AMP | Lithospermum erythrorhizon | |
CoA | does not act as cofactor, but has some stimulatory effect | Lithospermum erythrorhizon |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Lithospermum erythrorhizon | 5737 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-hydroxybenzaldehyde + NAD+ + H2O | Lithospermum erythrorhizon | best substrate tested, non beta-oxidative pathway rather than beta-oxidation | 4-hydroxybenzoate + NADH + H+ | - |
? | |
4-hydroxybenzaldehyde + NAD+ + H2O | Lithospermum erythrorhizon M18 | best substrate tested, non beta-oxidative pathway rather than beta-oxidation | 4-hydroxybenzoate + NADH + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Lithospermum erythrorhizon | - |
- |
- |
Lithospermum erythrorhizon M18 | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cell culture | - |
Lithospermum erythrorhizon | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-hydroxybenzaldehyde + NAD+ + H2O | very low activity | Lithospermum erythrorhizon | 2-hydroxybenzoate + NADH + H+ | - |
? | |
2-hydroxybenzaldehyde + NAD+ + H2O | very low activity | Lithospermum erythrorhizon M18 | 2-hydroxybenzoate + NADH + H+ | - |
? | |
3-hydroxybenzaldehyde + NAD+ + H2O | 48% of the activity compared to 4-hydroxybenzaldehyde | Lithospermum erythrorhizon | 3-hydroxybenzoate + NADH + H+ | - |
? | |
3-hydroxybenzaldehyde + NAD+ + H2O | 48% of the activity compared to 4-hydroxybenzaldehyde | Lithospermum erythrorhizon M18 | 3-hydroxybenzoate + NADH + H+ | - |
? | |
4-hydroxybenzaldehyde + NAD+ + H2O | best substrate tested, non beta-oxidative pathway rather than beta-oxidation | Lithospermum erythrorhizon | 4-hydroxybenzoate + NADH + H+ | - |
? | |
4-hydroxybenzaldehyde + NAD+ + H2O | best substrate tested, non beta-oxidative pathway rather than beta-oxidation | Lithospermum erythrorhizon M18 | 4-hydroxybenzoate + NADH + H+ | - |
? | |
benzaldehyde + NAD+ + H2O | 37.5% of the activity compared to 4-hydroxybenzaldehyde | Lithospermum erythrorhizon | benzoate + NADH + H+ | - |
? | |
benzaldehyde + NAD+ + H2O | 37.5% of the activity compared to 4-hydroxybenzaldehyde | Lithospermum erythrorhizon M18 | benzoate + NADH + H+ | - |
? | |
vanillin + NAD+ + H2O | 12.7% of the activity compared to 4-hydroxybenzaldehyde | Lithospermum erythrorhizon | vanillate + NADH | - |
? | |
vanillin + NAD+ + H2O | 12.7% of the activity compared to 4-hydroxybenzaldehyde | Lithospermum erythrorhizon M18 | vanillate + NADH | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | absolute requirement, can not be replaced by NADP+ | Lithospermum erythrorhizon |