Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.2.1.63 extracted from

  • Davey, J.F.; Trudgill, P.W.
    The metabolism of trans-cyclohexan-1,2-diol by an Acinetobacter species (1977), Eur. J. Biochem., 74, 115-127.
    View publication on PubMed

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
158000
-
gel filtration Acinetobacter sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6-oxohexanoate + NADP+ + H2O Nocardia globerula
-
adipate + NADPH
-
?
6-oxohexanoate + NADP+ + H2O Acinetobacter sp.
-
adipate + NADPH
-
?
6-oxohexanoate + NADP+ + H2O Nocardia globerula CL1
-
adipate + NADPH
-
?

Organism

Organism UniProt Comment Textmining
Acinetobacter sp.
-
-
-
Acinetobacter sp. NCIB 9871
-
-
-
Acinetobacter sp. TD63
-
-
-
Nocardia globerula
-
-
-
Nocardia globerula CL1
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Acinetobacter sp.

Source Tissue

Source Tissue Comment Organism Textmining
cell culture
-
Nocardia globerula
-
cell culture strain TD63 only inducible for enzyme synthesis in the presence of trans-cyclohexan-1,2-diol-containing growth media Acinetobacter sp.
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
7.7
-
-
Acinetobacter sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6-oxohexanoate + NADP+ + H2O
-
Nocardia globerula adipate + NADPH
-
?
6-oxohexanoate + NADP+ + H2O
-
Acinetobacter sp. adipate + NADPH
-
?
6-oxohexanoate + NADP+ + H2O
-
Nocardia globerula CL1 adipate + NADPH
-
?

Cofactor

Cofactor Comment Organism Structure
NADP+
-
Acinetobacter sp.