Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Disulfiram | 0.01 mM; 0.01 mM; 0.01 mM | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0004 | - |
3,4-dihydroxyphenylacetaldehyde | isozyme ALDH1A1 | Homo sapiens | |
0.001 | - |
3,4-dihydroxyphenylacetaldehyde | isozyme ALDH2 from liver | Homo sapiens | |
0.0026 | - |
3,4-dihydroxyphenylacetaldehyde | isozyme ALDH9A1 | Homo sapiens | |
0.0042 | - |
3,4-dihydroxyphenylacetaldehyde | isozyme ALDH1A1 from brain | Homo sapiens | |
0.015 | - |
3,4-dihydroxyphenylacetaldehyde | isozyme ALDH3A1 | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Homo sapiens | 5829 | - |
mitochondrion | - |
Homo sapiens | 5739 | - |
nucleus | - |
Homo sapiens | 5634 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P30838 | - |
- |
Homo sapiens | P43353 | - |
- |
Homo sapiens | P47895 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Homo sapiens | - |
liver | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3,4-dihydroxyphenylacetaldehyde + NAD+ + H2O | - |
Homo sapiens | 3,4-dihydroxyphenylacetate + NADH + H+ | - |
? | |
3,4-dihydroxyphenylglycolaldehyde + NAD+ + H2O | - |
Homo sapiens | 3,4-dihydroxyphenylglycolate + NADH + H+ | - |
? | |
retinal + NAD+ + H2O | preferred substrate of isozyme ALDH1A3 | Homo sapiens | retinoic acid + NADH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Aldh1a3 | - |
Homo sapiens |
ALDH3A1 | - |
Homo sapiens |
Aldh3b1 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | required | Homo sapiens |