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Literature summary for 1.2.1.5 extracted from

  • Choi, S.D.; Joo, C.N.
    Purification and characterization of the bovine cerebral mitochondrial aldehyde dehydrogenase (1991), Korean Biochem. J., 24, 224-230.
No PubMed abstract available
Search for more literature for 1.2.1.5

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.15
-
 5-hydroxyindole-3-acetaldehyde reaction with NAD+ Bos taurus
0.39
-
 3,4-dihydroxyphenyl acetaldehyde reaction with NAD+ Bos taurus
0.43
-
 NAD+ reaction with propanal Bos taurus
0.5
-
 Indole-3-acetaldehyde reaction with NAD+ Bos taurus
0.61
-
 3,4-dihydroxyphenyl benzaldehyde reaction with NAD+ Bos taurus
2
-
 propanal reaction with NAD+ Bos taurus
6.25
-
 NADP+ reaction with propanal Bos taurus
6.58
-
 acetaldehyde reaction with NAD+ Bos taurus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion membrane Bos taurus 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
61000
-
 4 * 61000, SDS-PAGE Bos taurus
250000
-
 gel filtration Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Bos taurus the membrane bound enzyme may act as barrier when the aldehyde concentration in cytosol is high ?
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein
-
 Bos taurus

Purification (Commentary)

Purification (Comment) Organism
partial Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
telencephalon
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
18.92
-
-
 Bos taurus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3,4-dihydroxymandelaldehyde + NAD+ + H2O
-
 Bos taurus 3,4-dihydroxyphenylmandelate + NADH + H+
-
 ?
3,4-dihydroxyphenylacetaldehyde + NAD+
-
 Bos taurus 3,4-dihydroxyphenylacetate + NADH
-
 ?
5-hydroxyindole-3-acetyldehyde + NAD+ + H2O
-
 Bos taurus 5-hydroxyindole-3-acetate + NADH + H+
-
 ?
acetaldehyde + NAD+ + H2O
-
 Bos taurus acetate + NADH + H+
-
 ?
an aldehyde + NADP+ + H2O
-
 Bos taurus a carboxylate + NADPH + H+
-
 r
indole-3-acetaldehyde + NAD+ + H2O
-
 Bos taurus indole-3-acetate + NADH + H+
-
 ?
additional information the membrane bound enzyme may act as barrier when the aldehyde concentration in cytosol is high Bos taurus ?
-
 ?
propanal + NAD+ + H2O
-
 Bos taurus propionate + NADH + H+
-
 ?

Subunits

Subunits Comment Organism
tetramer 4 * 61000, SDS-PAGE Bos taurus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
9 9.5
-
 Bos taurus