Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Amines | several amines stimulate activity | Homo sapiens | |
DL-2-amino-1-propanol | required, best activator of the reaction | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
40000 | - |
SDS-PAGE | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
methylglyoxal + NADP+ + H2O | Homo sapiens | contributes to the detoxification of methylglyoxal | pyruvate + NADPH | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
methylglyoxal + NADP+ + H2O | - |
Homo sapiens | pyruvate + NADPH | - |
? | |
methylglyoxal + NADP+ + H2O | contributes to the detoxification of methylglyoxal | Homo sapiens | pyruvate + NADPH | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | - |
Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
9.5 | - |
- |
Homo sapiens |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
8.5 | 10 | very low activity at physiological pH | Homo sapiens |