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Literature summary for 1.2.1.4 extracted from

  • Mihasan, M.; Stefan, M.; Hritcu, L.; Artenie, V.; Brandsch, R.
    Evidence of a plasmid-encoded oxidative xylose-catabolic pathway in Arthrobacter nicotinovorans pAO1 (2013), Res. Microbiol., 164, 22-30.
    View publication on PubMed
Search for more literature for 1.2.1.4

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Paenarthrobacter nicotinovorans

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0022
-
 NADP+ pH 8.4, 28°C, cosubstrate butyraldehyde Paenarthrobacter nicotinovorans
0.11
-
 Glutaraldehyde pH 8.4, 28°C, cosubstrate NADP+ Paenarthrobacter nicotinovorans
0.15
-
 Butyraldehyde pH 8.4, 28°C, cosubstrate NADP+ Paenarthrobacter nicotinovorans
0.65
-
 glyceraldehyde pH 8.4, 28°C, cosubstrate NADP+ Paenarthrobacter nicotinovorans
1.26
-
 NAD+ pH 8.4, 28°C, cosubstrate butyraldehyde Paenarthrobacter nicotinovorans
1.5
-
 propionaldehyde pH 8.4, 28°C, cosubstrate NADP+ Paenarthrobacter nicotinovorans
2.1
-
 benzaldehyde pH 8.4, 28°C, cosubstrate NADP+ Paenarthrobacter nicotinovorans
2.5
-
 acetaldehyde pH 8.4, 28°C, cosubstrate NADP+ Paenarthrobacter nicotinovorans
4.2
-
 formaldehyde pH 8.4, 28°C, cosubstrate NADP+ Paenarthrobacter nicotinovorans

Organism

Organism UniProt Comment Textmining
Paenarthrobacter nicotinovorans
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetaldehyde + NADP+ + H2O
-
 Paenarthrobacter nicotinovorans acetate + NADPH + H+
-
 ?
benzaldehyde + NADP+ + H2O
-
 Paenarthrobacter nicotinovorans benzoate + NADPH + H+
-
 ?
butyraldehyde + NAD+ + H2O
-
 Paenarthrobacter nicotinovorans butyrate + NADH + H+
-
 ?
butyraldehyde + NADP+ + H2O
-
 Paenarthrobacter nicotinovorans butyrate + NADPH + H+
-
 ?
formaldehyde + NADP+ + H2O
-
 Paenarthrobacter nicotinovorans formate + NADPH + H+
-
 ?
glutaraldehyde + NADP+ + H2O
-
 Paenarthrobacter nicotinovorans glutarate + NADPH + H+
-
 ?
glyceraldehyde + NADP+ + H2O
-
 Paenarthrobacter nicotinovorans glycerate + NADPH + H+
-
 ?
propionaldehyde + NADP+ + H2O
-
 Paenarthrobacter nicotinovorans propanoate + NADPH + H+
-
 ?

Synonyms

Synonyms Comment Organism
ALDH
-
 Paenarthrobacter nicotinovorans

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.33
-
 formaldehyde pH 8.4, 28°C, cosubstrate NADP+ Paenarthrobacter nicotinovorans
0.65
-
 Butyraldehyde pH 8.4, 28°C, cosubstrate NADP+ Paenarthrobacter nicotinovorans
0.75
-
 acetaldehyde pH 8.4, 28°C, cosubstrate NADP+ Paenarthrobacter nicotinovorans
1.02
-
 NADP+ pH 8.4, 28°C, cosubstrate butyraldehyde Paenarthrobacter nicotinovorans
1.2
-
 propionaldehyde pH 8.4, 28°C, cosubstrate NADP+ Paenarthrobacter nicotinovorans
1.35
-
 glyceraldehyde pH 8.4, 28°C, cosubstrate NADP+ Paenarthrobacter nicotinovorans
3.1
-
 NAD+ pH 8.4, 28°C, cosubstrate butyraldehyde Paenarthrobacter nicotinovorans
3.92
-
 Glutaraldehyde pH 8.4, 28°C, cosubstrate NADP+ Paenarthrobacter nicotinovorans
4.52
-
 benzaldehyde pH 8.4, 28°C, cosubstrate NADP+ Paenarthrobacter nicotinovorans

Cofactor

Cofactor Comment Organism Structure
NAD+ preference for NADP+ Paenarthrobacter nicotinovorans
NADP+ preference for NADP+ Paenarthrobacter nicotinovorans

kcat/KM [mM/s]

kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
0.09
-
 formaldehyde pH 8.4, 28°C, cosubstrate NADP+ Paenarthrobacter nicotinovorans
0.2
-
 glyceraldehyde pH 8.4, 28°C, cosubstrate NADP+ Paenarthrobacter nicotinovorans
0.21
-
 benzaldehyde pH 8.4, 28°C, cosubstrate NADP+ Paenarthrobacter nicotinovorans
0.3
-
 acetaldehyde pH 8.4, 28°C, cosubstrate NADP+ Paenarthrobacter nicotinovorans
0.35
-
 Glutaraldehyde pH 8.4, 28°C, cosubstrate NADP+ Paenarthrobacter nicotinovorans
0.43
-
 Butyraldehyde pH 8.4, 28°C, cosubstrate NADP+ Paenarthrobacter nicotinovorans
0.8
-
 propionaldehyde pH 8.4, 28°C, cosubstrate NADP+ Paenarthrobacter nicotinovorans
2.4
-
 NAD+ pH 8.4, 28°C, cosubstrate butyraldehyde Paenarthrobacter nicotinovorans
46
-
 NADP+ pH 8.4, 28°C, cosubstrate butyraldehyde Paenarthrobacter nicotinovorans