Literature summary for 1.2.1.31 extracted from

Ford, R.A.; Bhattacharjee, J.K.
Molecular properties of the lys1+ gene and the regulation of.alpha-aminoadipate reductase in Schizosaccharomyces pombe (1995), Curr. Genet., 28, 131-137.

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Cloned(Commentary)

Cloned (Comment)	Organism
two genes, lys1+ and lys7+ are required for the synthesis of the enzyme, some regions of the enzyme sequence are similar to the sequence of Saccharomyces cerevisiae, e.g. Schizosaccharomyces pombe enzyme residues 345 through 385, and 449 through 470	Schizosaccharomyces pombe

Inhibitors

Inhibitors	Comment	Organism	Structure
L-lysine	20% inhibition at 50 mM	Saccharomyces cerevisiae
L-lysine	54% inhibition at 1 mM and 80% inhibition at 4 mM	Schizosaccharomyces pombe

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	-	-	-
Schizosaccharomyces pombe	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-2-aminoadipate + NADPH	in presence of ATP + Mg2+	Saccharomyces cerevisiae	L-2-aminoadipate 6-semialdehyde + NADP+ + H2O	-	?

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Release 2023.1 (January 2023)