Literature summary for 1.2.1.3 extracted from

Lee, S.; Park, D.J.; Yoon, J.; Bang, S.H.; Kim, Y.H.; Min, J.
Formaldehyde treatment using overexpressed aldehyde dehydrogenase 6 from recombinant Saccharomyces cerevisiae (2018), J. Nanosci. Nanotechnol., 18, 2979-2985 .

Search for more literature for 1.2.1.3

Application

Application	Comment	Organism
additional information	enzyme ALD6 can potentially be used to treat hazardous substances to remove formaldehyde	Saccharomyces cerevisiae

Cloned(Commentary)

Cloned (Comment)	Organism
gene ALD6, functional recombinant overexpression of C-terminally GFP-tagged enzyme from vector pYES2 under control of GAL1 promoter in Saccharomyces cerevisiae strain MBTL-SYL-1 in cytosol	Saccharomyces cerevisiae

Protein Variants

Protein Variants	Comment	Organism
additional information	construction of an ALD6 dominant negative strain that is catalytically inactive, catalytic residues of the ALD6 gene are deleted	Saccharomyces cerevisiae

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytosol	-	Saccharomyces cerevisiae	5829	-

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	P54115	-	-
Saccharomyces cerevisiae ATCC 204508	P54115	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
formaldehyde + NAD+ + H2O	-	Saccharomyces cerevisiae	formate + NADH + H+	-	?
formaldehyde + NAD+ + H2O	-	Saccharomyces cerevisiae ATCC 204508	formate + NADH + H+	-	?
additional information	to assess the degree of formaldehyde degradation, luminescence measurements in Vibrio fischeri for formaldehyde toxicity are conducted	Saccharomyces cerevisiae	?	-	-
additional information	to assess the degree of formaldehyde degradation, luminescence measurements in Vibrio fischeri for formaldehyde toxicity are conducted	Saccharomyces cerevisiae ATCC 204508	?	-	-

Synonyms

Synonyms	Comment	Organism
ALD6	-	Saccharomyces cerevisiae
aldehyde dehydrogenase 6	-	Saccharomyces cerevisiae

Cofactor

Cofactor	Comment	Organism	Structure
NAD+	-	Saccharomyces cerevisiae

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Release 2023.1 (January 2023)