Literature summary for 1.2.1.3 extracted from

Goldstein, D.S.; Sullivan, P.; Cooney, A.; Jinsmaa, Y.; Kopin, I.J.; Sharabi, Y.
Rotenone decreases intracellular aldehyde dehydrogenase activity: implications for the pathogenesis of Parkinsons disease (2015), J. Neurochem., 133, 14-25.

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Inhibitors

Inhibitors	Comment	Organism	Structure
benomyl	-	Rattus norvegicus
additional information	not inhibited by rotenone	Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
3,4-dihydroxyphenylacetaldehyde + NAD+ + H2O	Rattus norvegicus	-	3,4-dihydroxyphenylacetic acid + NADH + H+	-	?

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
PC-12 cell	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3,4-dihydroxyphenylacetaldehyde + NAD+ + H2O	-	Rattus norvegicus	3,4-dihydroxyphenylacetic acid + NADH + H+	-	?

Synonyms

Synonyms	Comment	Organism
ALDH2	-	Rattus norvegicus

Cofactor

Cofactor	Comment	Organism	Structure
NAD+	-	Rattus norvegicus

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Release 2023.1 (January 2023)