Application | Comment | Organism |
---|---|---|
medicine | in human capacitance vessels ALDH2 is s a key enzyme for the biotransformation of the frequently used antianginal drug nitroglycerin | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-ethoxycyclopropanol | - |
Homo sapiens | |
Chloral hydrate | - |
Homo sapiens | |
cyanamide | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Homo sapiens | 5739 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
57000 | - |
determined by SDS-PAGE and Western Blot analysis | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
an aldehyde + NAD+ + H2O | Homo sapiens | - |
an acid + NADH + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
vein | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.00088 | - |
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
an aldehyde + NAD+ + H2O | - |
Homo sapiens | an acid + NADH + H+ | - |
? | |
glyceryl trinitrate + NADH + H+ | - |
Homo sapiens | 1,2-glyceryl dinitrate + nitrite + NAD+ | - |
? | |
propanal + NAD+ + H2O | activity assay | Homo sapiens | propanoic acid + NADH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
aldehyde dehydrogenase type 2 | - |
Homo sapiens |
ALDH2 | - |
Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.8 | - |
activity assay | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Homo sapiens |