Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-hydroxynon-2-enal | 10% inhibition at 0.05 mM | Homo sapiens | |
4-oxonon-2-enal | 90% inhibition at 0.05 mM | Homo sapiens | |
4-oxonon-2-enoic acid | 90% inhibition at 0.05 mM | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.183 | - |
glutathione-4-oxonon-2-enal | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
56000 | - |
SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
p-hydroxyacetophenone Sepharose affinity column | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-hydroxynon-2-enal + NAD+ | - |
Homo sapiens | 4-hydroxynon-2-enoic acid + NADH | - |
? | |
4-oxonon-2-enal + NAD+ + H2O | - |
Homo sapiens | 4-oxonon-2-enoic acid + NADH | - |
? | |
glutathione-4-oxonon-2-enal + NAD+ + H2O | - |
Homo sapiens | glutathione-4-oxonon-2-enoic acid + NADH | - |
? |
Synonyms | Comment | Organism |
---|---|---|
aldehyde dehydrogenase | - |
Homo sapiens |
hALDH2 | - |
Homo sapiens |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.04 | - |
glutathione-4-oxonon-2-enal | 50 mM sodium phosphate buffer pH 7.4, 1 mM NAD+, 37°C | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Homo sapiens |