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Literature summary for 1.2.1.23 extracted from

  • Fujii, E.; Iwase, H.; Ishii-Karakasa, I.; Yajima, Y.; Hotta, K.
    The presence of 2-keto-3-deoxygluconic acid and oxoaldehyde dehydrogenase activity in human erythrocytes (1995), Biochem. Biophys. Res. Commun., 210, 852-857.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2-dehydro-3-deoxy-D-glucose + NAD+ + H2O Homo sapiens
-
2-dehydro-3-deoxy-D-gluconate + NADH + H+ levels in diabetic patients are significantly higher compared with healthy subjects in both erythrocytes and plasma ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
erythrocyte
-
Homo sapiens
-
plasma
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-dehydro-3-deoxy-D-glucose + NAD+ + H2O
-
Homo sapiens 2-dehydro-3-deoxy-D-gluconate + NADH + H+ levels in diabetic patients are significantly higher compared with healthy subjects in both erythrocytes and plasma ?
2-oxoaldehydes + NAD+ + H2O
-
Homo sapiens 2-oxo acids + NADH
-
?

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Homo sapiens