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Literature summary for 1.2.1.16 extracted from

  • Walsh, J.M.; Clark, J.B.
    Studies on the control of 4-aminobutyrate metabolism in synaptosomal and free rat brain mitochondria (1976), Biochem. J., 160, 147-157.
    View publication on PubMedView publication on EuropePMC

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.4
-
succinate semialdehyde synaptosomes Rattus norvegicus
1.5
-
succinate semialdehyde mitochondria of non-synaptic origin Rattus norvegicus
9.4
-
NAD+ mitochondria of non-synaptic origin Rattus norvegicus
17
-
NAD+ synaptosomes Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion of non-synaptic origin Rattus norvegicus 5739
-
synaptosome
-
Rattus norvegicus
-
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
Wistar strain
-
Rattus norvegicus Wistar
-
Wistar strain
-

Purification (Commentary)

Purification (Comment) Organism
chromatography on Celite 535 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
succinate semialdehyde + NAD+ + H2O
-
Rattus norvegicus succinate + NADH + H+
-
r
succinate semialdehyde + NAD+ + H2O
-
Rattus norvegicus Wistar succinate + NADH + H+
-
r
succinate semialdehyde + NADP+ + H2O
-
Rattus norvegicus succinate + NADPH + H+
-
?
succinate semialdehyde + NADP+ + H2O
-
Rattus norvegicus Wistar succinate + NADPH + H+
-
?

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Rattus norvegicus