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Literature summary for 1.2.1.16 extracted from

  • Sims, K.L.; Davis, G.A.
    Subcellular distribution of succinate-semialdehyde dehydrogenase in rat brain (1973), Eur. J. Biochem., 35, 450-453.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
5,5-dipropylpentanoate
-
Rattus norvegicus
dipropylacetate
-
Rattus norvegicus
p-Hydroxybenzaldehyde
-
Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Rattus norvegicus 5739
-
synaptosome
-
Rattus norvegicus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
succinate semialdehyde + NADP+ + H2O Rattus norvegicus involved in the degradation of gamma-aminobutyrate succinate + NADPH + H+
-
?
succinate semialdehyde + NADP+ + H2O Rattus norvegicus Sprague-Dawley involved in the degradation of gamma-aminobutyrate succinate + NADPH + H+
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
Sprague-Dawley strain
-
Rattus norvegicus Sprague-Dawley
-
Sprague-Dawley strain
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
succinate semialdehyde + NADP+ + H2O
-
Rattus norvegicus succinate + NADPH + H+
-
?
succinate semialdehyde + NADP+ + H2O involved in the degradation of gamma-aminobutyrate Rattus norvegicus succinate + NADPH + H+
-
?
succinate semialdehyde + NADP+ + H2O
-
Rattus norvegicus Sprague-Dawley succinate + NADPH + H+
-
?
succinate semialdehyde + NADP+ + H2O involved in the degradation of gamma-aminobutyrate Rattus norvegicus Sprague-Dawley succinate + NADPH + H+
-
?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
-
2 substancial progressive loss of activity, sucrose fractions Rattus norvegicus
25
-
substancial progressive loss of activity, sucrose fractions Rattus norvegicus