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Literature summary for 1.2.1.12 extracted from

  • Kundu, S.; Roy, D.
    Computational study of glyceraldehyde-3-phosphate dehydrogenase of Entamoeba histolytica: implications for structure-based drug design (2007), J. Biomol. Struct. Dyn., 25, 25-33.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
GADPH in complex wit NAD+, computational modelling Entamoeba histolytica

Inhibitors

Inhibitors Comment Organism Structure
chalepin natural inhibitor of GAPDH Entamoeba histolytica

Organism

Organism UniProt Comment Textmining
Entamoeba histolytica
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-glyceraldehyde 3-phosphate + phosphate + NAD+
-
Entamoeba histolytica 3-phospho-D-glyceroyl phosphate + NADH + H+
-
?

Subunits

Subunits Comment Organism
dimer x-ray crystallography Entamoeba histolytica

Synonyms

Synonyms Comment Organism
GAPDH
-
Entamoeba histolytica

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Entamoeba histolytica