Literature summary for 1.2.1.12 extracted from

Mounaji, K.; Vlassi, M.; Erraiss, N.E.; Wegnez, M.; Serrano, A.; Soukri, A.
In vitro effect of metal ions on the activity of two amphibian glyceraldehyde-3-phosphate dehydrogenases: potential metal binding sites (2003), Comp. Biochem. Physiol. B, 135B, 241-254.

No PubMed abstract available

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Cloned(Commentary)

Cloned (Comment)	Organism
-	Xenopus laevis
-	Pleurodeles waltl

Inhibitors

Inhibitors	Comment	Organism	Structure
CdCl2	20 mM, about 30% inhibition. 10 mM, 70% inhibition	Pleurodeles waltl
CdCl2	20 mM, about 65% inhibition	Xenopus laevis
CuSO4	0.001 mM, 90% inhibition within 2 min	Pleurodeles waltl
CuSO4	0.001 mM, 70% inhibition in 2 min	Xenopus laevis
ZnSO4	20 mM, 70% inhibition	Pleurodeles waltl
ZnSO4	20 mM, 50% inhibition	Xenopus laevis

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
35000	-	4 * 35000, SDS-PAGE	Xenopus laevis
37000	-	4 * 37000, SDS-PAGE	Pleurodeles waltl

Organism

Organism	UniProt	Comment	Textmining
Pleurodeles waltl	Q8AXB5	-	-
Xenopus laevis	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Xenopus laevis
-	Pleurodeles waltl

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
D-glyceraldehyde 3-phosphate + phosphate + NAD+	-	Xenopus laevis	3-phospho-D-glyceroyl phosphate + NADH	-	?
D-glyceraldehyde 3-phosphate + phosphate + NAD+	-	Pleurodeles waltl	3-phospho-D-glyceroyl phosphate + NADH	-	?

Subunits

Subunits	Comment	Organism
tetramer	4 * 37000, SDS-PAGE	Pleurodeles waltl
tetramer	4 * 35000, SDS-PAGE	Xenopus laevis

Synonyms

Synonyms	Comment	Organism
GAPDH	-	Xenopus laevis
GAPDH	-	Pleurodeles waltl

Cofactor

Cofactor	Comment	Organism	Structure
NAD+	-	Xenopus laevis
NAD+	-	Pleurodeles waltl

pI Value

Organism	Comment	pI Value Maximum	pI Value
Pleurodeles waltl	isoelectric focusing	-	6.9
Xenopus laevis	isoelectric focusing	-	7.1

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Release 2023.1 (January 2023)