Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2,3-diphosphoglycerate | - |
Homo sapiens | |
ATP | noncompetitive inhibitor | Homo sapiens | |
D-glyceraldehyde 3-phosphate | substrate inhibition | Homo sapiens | |
NADH | - |
Homo sapiens | |
NO3- | uncompetitive inhibitor with NAD+, dead end inhibitor | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | isolated from human erytrocyt ghosts | Homo sapiens | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glyceraldehyde 3-phosphate + phosphate + NAD+ | Homo sapiens | glycolytic enzyme | 3-phospho-D-glyceroyl phosphate + NADH | - |
? | |
additional information | Homo sapiens | enzyme is regulated by ATP and by D-glyceraldehyde 3-phosphate | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
D-glyceraldehyde 3-phosphate + phosphate + NAD+ = 3-phospho-D-glyceroyl phosphate + NADH + H+ | ordered ter bi mechanism characterized by the sequential addition of NAD+, glyceraldehyde 3-phosphate and phosphate to the enzyme and the sequential release of 3-phospho-D-glyceroyl phosphate and NADH from the enzyme | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
erythrocyte | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
98 | - |
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glyceraldehyde 3-phosphate + phosphate + NAD+ | - |
Homo sapiens | 3-phospho-D-glyceroyl phosphate + NADH | - |
? | |
D-glyceraldehyde 3-phosphate + phosphate + NAD+ | glycolytic enzyme | Homo sapiens | 3-phospho-D-glyceroyl phosphate + NADH | - |
? | |
additional information | enzyme is regulated by ATP and by D-glyceraldehyde 3-phosphate | Homo sapiens | ? | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Homo sapiens |